This cross-sectional study examines mortality from radiation-related and non–radiation-related cancers among aircrew members and other aviation workers in the US.
This randomized clinical trial examines the efficacy of a culturally and medically tailored meal program on the incidence of hospitalizations and emergency department visits among Indigenous communities.
This review examines the evidence for continuous glucose monitoring use beyond type 1 diabetes or pregnancy, explores its usefulness as a behavior change aid, and critically assesses its expanding role in the care of people with dysglycemia.
This randomized clinical trial aims to determine whether autonomous oxygen titration increases the proportion of time spent in a targeted normoxemia range compared with usual care in acutely ill adults.
This JAMA Internal Medicine Patient Page describes how glucagon-like peptide-1 (GLP-1) receptor agonists work and what behaviors to adopt while using them.
This cohort study compares treatment-associated weight loss and rates of gastrointestinal adverse events among adults with overweight or obesity receiving tirzepatide or semaglutide labeled for type 2 diabetes in a clinical setting.
Aircrew members represent a unique occupational group exposed to a constellation of known and probable carcinogens, including cosmic ionizing radiation (CIR) at cruising altitude, UV-A radiation penetrating cockpit windows (for pilots), and circadian rhythm disruption from night-shift work and repeated time zone crossing. Whether these exposures translate to measurably elevated cancer mortality has remained a surprisingly difficult question to answer. Prior studies have relied primarily on cancer incidence rather than mortality and have been hampered by confounding from socioeconomic and lifestyle factors. Health screening common in aviation creates a healthy worker effect that suppresses apparent mortality risk, making any observed excess harder to detect and, therefore, more meaningful when found. The study by Patel et al brings important new evidence to bear on this question.
This post hoc analysis of a randomized clinical trial assesses changes in cardiometabolic parameters by degree of weight regain after withdrawal of tirzepatide.
This cohort study investigates the association of alpha-gal syndrome prevalence among patients with blood type O blood and rates of allergic transfusion reaction.