This cohort study compares treatment-associated weight loss and rates of gastrointestinal adverse events among adults with overweight or obesity receiving tirzepatide or semaglutide labeled for type 2 diabetes in a clinical setting.
This randomized clinical trial aims to determine whether a direct oral penicillin challenge is noninferior to the standard of care of penicillin skin testing followed by an oral challenge in patients with a low-risk penicillin allergy.
This Narrative Review summarizes current evidence and explores emerging science on the prevention and treatment of dementia to inform clinical decision-making.
This cohort study examines the association of periconceptional use of glucagon-like peptide 1 (GLP-1) receptor agonists or other noninsulin second-line antidiabetic medications with increased risk of major congenital malformations.
This cohort study aims to determine whether use of glucagon-like peptide 1 receptor agonists are associated with lower risk of developing cirrhosis and its complications, including decompensation and hepatocellular cancer, among patients with metabolic dysfunction-associated steatotic liver disease.
This French cohort study evaluates in-hospital mortality and adverse effects among older adults (≥75 years) who waited overnight in the emergency department for a bed in a hospital ward.
This cohort study examines the associations between incident dementia and long-term fine particulate matter expressed as total mass and fine particulate matter from unique emission sources.
This cross-sectional study assesses the ability of a large language model to process medical data and display clinical reasoning compared with the ability of attending physicians and residents.